s-Dashboard has four different types of layouts, which can be used in combination. For both Horizontal and Vertical, you can additional frames that will be visible to users. For Main with Sidebar and Main with Bottom Bar, you can add additional frames, but they will not be visible. They will, however, be available to swap with adjacent panels, as described in the topic Swapping Panels.
You can also enclose sub-frames in layouts, to create more complex layouts.
Vertical with two additional frames added: